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To understand the complex pathophysiology of the disease and the evaluation of potential specific therapies, researchers have developed several murine models and generation of transgenic mouse clones as a solution for the absence of a natural animal pattern for SCD [130,131,132]

Hepatic uptake of gamma-butyrobetaine, a precursor of carnitine biosynthesis, in rats

Several currently used cancer drugs exert their anticancer activity in part through covalent inhibition of TrxR 21 and two covalent TrxR inhibitors are currently in clinical trials 68

Wiley Interdiscip Rev Nanomed Nanobiotechnol

There is no set follow-up schedule