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Screening of potential anti-thrombotic ingredients from Salvia miltiorrhiza in zebrafish and by molecular docking

In a prospective cohort study of 36 patients with albuminuria who were initiated on sitagliptin 50 mg daily, patients experienced a significant change in both systolic and diastolic BP that was apparent after 6 months (baseline systolic BP 140 +/ 18 mmHg dropped to 129 +/ 17 mmHg and baseline diastolic BP 77 +/ 10 mmHg fell to 73 +/ 7 mmHg

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Tirzepatide, a newer dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) agonist, did not show a benefit in this analysis, which Jones said may be due to its more recent approval and smaller sample size

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