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Bregman is a board-certified foot and ankle surgeon with nearly 30 years in practice 15 of which have been in Las Vegas

While GLP-1 medications provide powerful support for weight management, the degree of weight loss depends heavily on adherence to a modest caloric deficit below total daily energy expenditure and on engaging in regular physical activity to increase caloric utilization, he explains

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It begins with dysfunctional transmembrane insulin receptor (as a result of lipidperoxidation)

It's worth noting, though, that any form of weight loss causes muscle loss, not just the kind that comes with weight loss drugs