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Cell Research 418 (2), 113269

Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, openlabel, parallelgroup study

B12 plays a crucial role in melanin synthesis , and its deficiency might disrupt this process, leading to hyperpigmentation

Using vented needles or introducing air displacement volume into the vial during withdrawal reduces the negative pressure that causes coring, extending both mechanical vial integrity and solution sterility

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