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At Flow Wellness, we see these reactions occur with either medication, although individual responses vary

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Cannabinoid Type-1 Receptor Antagonists The cannabinoid neurotransmitter system also affects the central control of appetite, with cannabinoid-1 receptor agonists increasing appetite and antagonists suppressing appetite [101]

Ceriello A, Novials A, Canivell S, La Sala L, Pujadas G, Esposito K, Testa R, Bucciarelli L, Rondinelli M, Genovese S: Simultaneous GLP-1 and insulin administration acutely enhances their vasodilatory, antiinflammatory, and antioxidant action in type 2 diabetes