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Enrolled participants receive the study medication for free along with regular medical monitoring

Leptin levels also drop significantly as fat mass decreases, signaling to your brain that energy reserves are depleted and conservation is necessary

Starting dose also mattered for tolerability

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Overall, compared with the large and growing amount of pre-clinical and mechanistic evidence highlighting the reward-modulating and thus potentially anti-addictive properties of GLP-1RAs, only a few studies have investigated thus far the potential use of these medications in clinical populations with alcohol- or other substance-use disorders