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Some research from Germany has shown that an even higher threshold (over 500 pg/mL) is necessary in early-to-mid pregnancy to maintain vitamin B12 levels throughout pregnancy, lactation, and to support an infants vitamin B12 status (via breast milk) through 6 months of age

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It was developed at Novo Nordisk and introduced to the literature by Raun and colleagues in 1998 under a title that has defined it ever since: the first selective growth hormone secretagogue

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Talk to a healthcare professional if you notice any significant or persistent cycle changes