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Human organic anion transporter 1B1 (OATP1B1/OATP-C) and 1B3 (OATP1B3/OATP-8) function as bidirectional carriers and do not mediate GSH-bile acid co-transport

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Such a covalent modification is supported by a previous report showing that non-sulfonic substituents at C-2 position (methylsulfone) failed to produce measurable cAMP responses 38 , consistent with our mutagenesis results, where C347 6.36b A mutation diminished the potency of compound 2 without affecting that of GLP-1 (Fig

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