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In clinical trials, participants who stopped semaglutide regained a significant portion of the weight theyd lost within about a year

It is not for women with normal ovarian reserve or Polycystic Ovary Syndrome (PCOS), for example

These include : Thyroid cancer: It isnt known if GLP-1s cause thyroid tumors in humans, but for now, anyone with a personal or family history of medullary thyroid carcinoma (a specific kind of thyroid cancer ) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should avoid taking retatrutide

*It is essential to note that while GLP-1s can contribute to weight loss, they should not be solely relied upon as a standalone solution

doi: 10.3390/metabo10120502 4 YangWLiuCLiZCuiM