Most consistent users report visible improvement in dark spots, acne scarring, and overall skin tone clarity within 6 to 8 weeks of daily use
Source 63: Acne vulgaris and risk of depression and anxiety: A meta-analytic review Source 64: Brain-Skin Connection: Stress, Inflammation and Skin Aging Source 65: 3,3-Diindolylmethane Modulates Estrogen Metabolism in Patients with Thyroid Proliferative Disease: A Pilot Study Source 66: 3,3'-Diindolylmethane suppresses the inflammatory response to lipopolysaccharide in murine macrophages Source 67: The Role of Estrogen Receptors and Their Signaling across Psychiatric Disorders Source 68: Glutathione
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doi: 10.1111/ijd.12999
It has cytoprotective, immunomodulatory, antioxidant, choleretic, and antiapoptotic properties [13]
