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Whether initiating GLP-1 RAs earlier - either concomitantly with surgery or immediately upon detecting early weight regain - could improve long-term outcomes remains to be investigated

Ouyang J, Cai Y, Song Y, Gao Z, Bai R, Wang A

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The peptide has also been reported to interact with central dopaminergic and serotonergic axes: rodent behavioral studies describe effects on neuroplasticity, GABAergic tone, and stress response