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The capacity of mitochondria to provide this support and their plasticity have been linked to circuit architecture, engagement and adaptation, with implications for learning and memory, reward and reinforcement, statetrait anxiety and motivation

Similarly, 12 weeks of progressive full body RT 3 times per week (3 sets of 10 reps, progression from 50%80% 1RM), in older humans lowers basal IL-6 levels, which may represent an adaptation to the exercise (Forti et al., 2014)

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