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Development and parasympathetic regulation in male and female adolescents with autism spectrum disorder: A two-timepoint longitudinal study

Tissue collectionAt the time of scheduled termination, animals are sacrificed as follows

By inhibiting the inflammatory pathway such as NF-B, PDEVs can downregulate the expression of inflammatory factors such as TNF-, IL-1 and IL-6, and improve the imbalance of reproductive microenvironment caused by inflammatory diseases (such as pelvic inflammatory disease and endometriosis) or oxidative stress ( ex vivo experiments with human primary T lymphocytes demonstrated LEVs ability to reduce pro-inflammatory cytokines and enhance anti-inflammatory molecules, thereby confirming that LEVs overinhibit the ERK1-2/NF-B signaling pathway to exert anti-inflammatory effects both in vitro and in vitro conditions (Raimondo et al., 2022)

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Biotechnol., vol