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2018;155(4):1164-1176e2

Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells

Safety Most retatrutide trial participants experienced minor side effects

Sex-dependent divergence in the effects of GLP-1 agonist exendin-4 on alcohol reinforcement and reinstatement in C57BL/6J mice

Researchers found that people taking these medications were less likely to develop substance use disorders involving alcohol, nicotine, cannabis, cocaine, opioids, and other drugs, while those already struggling with addiction experienced fewer overdoses, hospitalizations, emergency visits, and drug-related deaths