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Association between SOD deficiency and a number of pathologies has been observed in both animals and humans (Fig

Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study

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It inhibits the production of pro-inflammatory cytokines (TNF-alpha, IL-6, IL-12), modulates the polarization of macrophages towards the M2 (anti-inflammatory) phenotype, and stimulates collagen production in models of pulmonary and cutaneous fibrosis