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Like with methacholine, the extra methyl side group in bethanechol results in selectivity for muscarinic vs nicotinic receptors, and contributes to resistance to metabolism by cholinesterases

In the UK, hydroxocobalamin is the standard licensed preparation for injection, as recommended by NICE and the BNF, due to its superior retention in the body

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Some studies have suggested that allulose may cause an increase in gastrointestinal symptoms such as bloating and gas, especially when consumed in high doses

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