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Ongoing research aims to investigate the specific pathways and targets through which BV and its constituents exert their pharmacological effects, both beneficial and detrimental, to optimize its therapeutic potential while minimizing adverse reactions (Pandey et al., 2023a)

Another meta-analysis study of 12 randomized controlled trials involving non-dialysis patients revealed that biotic supplements did not significantly reduce the serum creatinine levels compared to the placebo group (Liu F

Similarly, albeit also in a small cohort, Comhair et al

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