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Waqas SA, Sohail MU, Saad M et al (2025) Efficacy of GLP-1 Receptor Agonists in Patients with Heart Failure and Mildly Reduced or Preserved Ejection Fraction: A Systematic Review and Meta-Analysis

The 8mg dose delivered 21.1% weight reduction

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In one study conducted in diet-induced obese mice, Reta not only led to significant reductions in body weightoften surpassing those seen with GLP-1-only therapiesbut also improved metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic fat content