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Enhanced interferon response to murine leukemia virus by ascorbic acid

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The attachment of IgE-allergen immune complexes to FcRI activates tyrosine kinases such as Lyn, Fyn, and Syk that subsequently phosphorylate a variety of signaling molecules such as LAT, SLP-76, and PLC-1 and lead to mast cell degranulation

Essentially, when NLRP3 activates, it causes caspase-1 activation, which in turn activates interleukin-1 (IL-1) and interleukin-18 (IL-18)