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This modification allows the peptide to bind to amylin receptor subtypes 1 and 3 in the brain, specifically in the area postrema of the hindbrain, producing sustained appetite reduction without the peaks and valleys that come with shorter-acting compounds

Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping

ML analyzed the data, LZ and CL interpreted the data, drafted the manuscript, GJ supervised the process, and critically revised the manuscript

Rats were intravitreally administered with LPS alone or in combination with GSSSG and sacrificed 48 h later, and then dissected retinas were immunostained for the microglial marker Iba1 (Fig