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A 2023 systematic review and meta-analysis of 82 RCTs (10,332 patients) examined probiotics for IBS symptoms, and for abdominal bloating or distension reported only very low certainty in the evidence for a benefit, with some specific combination probiotics and Bacillus strains showing potential signals.[5] Certainty grading reflects how confident the analysis is in the effect estimate

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Side effects [edit] Several side effects with diuretics and masking agents are: severe muscle cramps, heart rate irregularities, thrombosis, dehydration, and kidney failure