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Additionally, the long-term safety of high-dose L-carnitine use is not well-established , and there are ongoing debates about its potential risks

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In comparison with the animals in the control group, rats treated with 3 and 10 mg/kg of rimonabant had an increase in O 2 consumption of 18% and 49%, respectively, after 3 h

In preclinical research settings, it has attracted interest for its involvement in cellular energy regulation, NAD metabolism, and adipose-related metabolic signaling , positioning it within metabolic and longevity-focused research models