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doi: 10.3389/fendo.2020.00178 Received 13 December 2019 Accepted 12 March 2020 Published 03 April 2020 Volume 11 - 2020 Edited by Jens Juul Holst, University of Copenhagen, Denmark Reviewed by Alain Couvineau, Institut National de la Sant et de la Recherche Mdicale (INSERM), France

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10.1017/S0007114508939830 51 RiderS

Chemical Structure: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg(16 AAs) Alternative Names: Mitochondrial ORF CAS Number: Not Applicable WHAT IS MOTS-C MOTS-c is a small 16-amino acid peptide with a singular distinction: it is one of a handful of known Mitochondrial-Derived Peptides (MDPs)

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