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employed the LPS and CUMS-induced model to investigate the antidepressant effects of PSP and elucidate its underlying mechanism of action

Although the antioxidant capacity of flavonoids may be compromised after reacting with ROS, recent studies have shown that the oxidized derivatives of certain flavonoids can significantly enhance their original antioxidant properties by activating the NRF2/KEAP1 pathway and upregulating the cell's endogenous antioxidant capacity [423]

There is a clear need for more research in this area

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