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Network meta-analysis showed no evidence of differences among all possible comparisons for secondary outcomes (MCV, homocysteine levels, platelet counts, and WBC counts)
However, only 22% of the variation in MMA levels was explained by vitamin B12, estimated glomerular filtration rate, age, sex, and socioeconomic status, suggesting that other underlying disease was likely the reason for elevated MMA levels
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Mitochondrial energy: NAD+ is a critical electron carrier in the electron transport chain
It is contraindicated in certain conditions such as active malignancy and must be used cautiously in those with diabetes, prediabetes, or a history of pituitary disease, which is why careful screening and regular monitoring are essential
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