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High blood flow to the muscles may cause them pain

The article explains that GLP-1 receptor agonists slow the rate at which food leaves the stomach, so undigested food and carbohydrates ferment longer and release hydrogen sulfide and other volatile compounds

Healthy subjects in this phase 1 study who were given a 225 mg dose had a mean concentration of 22.1 g/mL at day 29 and those given 675 mg had a mean concentration of 24.1 g/mL at day 85