Cyanocobalamin (vitamin B12) is necessary for normal hematopoiesis and erythrocyte maturation, and also participates in a number of biochemical reactions that ensure the vital activity of the body - in the transfer of methyl groups, in the synthesis of nucleic acids, protein, in the exchange of amino acids, carbohydrates, lipids
10.5194/bg-10-3839-2013 78 TangW.DuanJ.ZhangY.LuoX
Tagliaferri V, Romualdi D, Scarinci E, Cicco SD, Florio CD, Immediata V, Tropea A, Santarsiero CM, Lanzone A, Apa R
Neuronal transmitters such as ACh and adenosine bind to their respective receptors on pericytesMRs for ACh and adenosine A 2A receptors for adenosinecausing pericyte hyperpolarization and increased CBF
All mice were from a C57BL/6 background and were group-housed and maintained in individual ventilated cages with standard bedding and enrichment in a temperature- and humidity-controlled room on a 12-h light:dark cycle (lights on 7:00) with AL access to food (standard diet, Scientific Animal Food Engineering, or 45% HFD) and water unless otherwise stated