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Adhering to best practices when taking GLP-1 medications ensures you receive the full therapeutic benefit whilst minimising potential side effects

It works by mimicking the natural hormone GLP-1, enhancing insulin secretion, suppressing glucagon release, slowing gastric emptying, and promoting satiety

Current clinical guidance does not recommend GLP-1 receptor agonists during breastfeeding due to insufficient safety data in lactating populations

Alterations in the volume of distribution and clearance resulting from other mechanisms of action (eg, reduced fat mass, changes in cytochrome P450 activity, and glomerular filtration rate) are key factors in determining pharmacokinetics

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Gupta V