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Some researchers theorize that the GIP component may actually help moderate some of the harsher GI effects of GLP-1 activation, which could partially explain why retatrutide compared to other agents does not always show proportionally worse GI profiles despite having three active mechanisms

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By slowing gastric emptying, GLP-1 injections make it easier to maintain a calorie deficit without feeling deprived

These findings of the three scientists together ushered in an era of GLP-based drugs for treating diabetes, with contributions by many from academia and industry

But a whole new arenadaily weight-loss pillsis changing the rules of the game once again