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Furthermore, current potential therapeutic strategies targeting inflammatory pathways are reviewed, including anti-inflammatory agents (e.g., cyclooxygenase-2 (COX-2) and NLRP3 inhibitors), antioxidants (such as N-acetylcysteine (NAC) and melatonin), probiotic modulation (via gut-brain axis (GBA) regulation), and precision therapies (such as mesenchymal stem cells (MSCs) and exosome-based approaches)

Major multinational pharmaceutical companies like Novo Nordisk and Eli Lilly have already seized significant market share with their continuously upgraded products

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108 SzczesniakT.KarabinL.SzczepankowskaM.WituchK

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema