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A study has shown that high expression of DPP-4 is not only found in intestinal epithelial brush border, but also in endothelial cells ( via renal elimination

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Separately, in the REDEFINE 4 head-to-head trial against tirzepatide, CagriSema produced approximately 20.2% body weight reduction at 84 weeks, compared with 23.6% for tirzepatide

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Patients who maintain higher protein intake and regular resistance training during treatment tend to preserve lean muscle mass better while losing fat