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Tissue remodeling continues even as symptoms resolve

These adverse effects stem from the entry of the cytoplasmic exonuclease TREX1 into the nucleus, which induces DNA cleavage [195], as well as the translocation of DNA repair factors such as Ku70, Ku80, and BRCA1 to the cytoplasm [190, 194]

Neuron 108, 801821

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PT-141 is thought to increase sexual desire in both men and women by activating the MC4R in the brain, which ultimately leads to an increase in the production of neurotransmitters like dopamine in specific brain areas related to libido and sex drive [7]