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Per the same safety document, the most commonly reported side effects are typically mild and tend to resolve after the first several weeks: nausea, vomiting, diarrhea, constipation, abdominal pain, upset stomach, reflux, headache, fatigue, and dizziness, along with possible injection-site swelling, redness, or itchiness

[DOI] [PubMed] [Google Scholar] 44.Shaddinger BC, Young MA, Billiard J, Collins DA, Hussaini A, Nino A

According to the ADA 2018 Guidelines [1], treatment for T2DM should start with monotherapy unless A1c is greater or equal than 9.0%, when dual therapy must be considered

Sublingual options Sublingual tirzepatide involves placing a formulation under the tongue for absorption through the oral mucosa