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This could lead to improved health outcomes for a broader population, ultimately contributing to better management of diabetes and obesity-related complications

Diabetologia 53 , S342 (2010)

The main mechanism of SGLT-2i is to act on the SGLT2 receptor of the proximal tubule, inhibit the reuptake of Na + and glucose, increase the excretion of glucose in urine to reduce blood glucose, and subsequently increase natriuria

The heart's high energy demands make it respond well to NAD+ replenishment [7]

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