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The results of several large randomized controlled trials indicated that maintaining blood glucose at near normal concentrations was the most important step in limiting the risk of diabetic neuropathy and lower extremity amputation (70-72)

Comprehensive monitoring should include assessment of therapeutic response and screening for potential adverse effects, particularly signs of malignancy given the angiogenic effects

Viner, R

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Clinical evidence of coenzyme Q10 pretreatment for women with diminished ovarian reserve undergoing IVF/ICSI: a systematic review and meta-analysis