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3.2.5 LRRK2 The leucine-rich repeat kinase 2 (LRRK2) participates in mitochondrial dynamics, oxidative stress, and lipid metabolism (160)

A related study found that LND and BPTES were able to induce glycolysis and inhibit glutamine metabolism, which was accompanied by significant mitochondrial damage, ultimately blocking energy supply and posing a threat to tumour survival, to efficiently kill tumours

To test the efficacy of ANS in vivo, SC-islets were treated with 25 nM ANS for 72 h and transplanted into hyperglycemic mice

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