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Cell 164 , 564578 (2016)

A medically supervised GLP-1 program allows providers to personalize care, adjust dosing, and monitor progress safely

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For example, in particulate matter exposure-related models, GLS1-mediated enhancement of glutaminolysis, together with alterations in local Gln/-KG levels, can be accompanied by enhanced M1-like polarization, and inhibition of GLS1 can alleviate this pro-inflammatory polarization trend (60)