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The consideration of cysteine during these simulations were important, as cytosolic cysteine is the rate limiting amino acid precursor for synthesis of GSH, via the -glutamylcysteine synthetase (GCS) enzyme, and this is a function of its reduced concentration compared to the other precursors, glycine and glutamate

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suis GGT has previously been shown to be an important factor degrading Gln, but also GSH

The company states it uses the arginate salt form, which the company positions for its potential gastric stability advantages over the acetate salt form commonly used in injectable preparations

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