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Body weight reduction averaged 5.5% in the liraglutide arm compared to 0.7% with placebo ( P = 0.003), while glycemic control improved as reflected by a mean HbA1c decrease of 5.7 mmol/mol ( P = 0.03)

The evidence: Unapproved peptides have little, if any, human clinical trial data supporting safety or efficacy

These actions can also result in muscle hypertrophy, and this boost in muscle mass improves the functional capacity of skeletal muscle

Gastrointestinal tolerability of once-weekly semaglutide 24 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss

The removal took effect seven days later, on April 22