glp 1 from hers Hims & tackles high GLP-1 prices in Super Bowl ad Hims & Hers Selling GLP-1

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D., Ringel, Y., & Slavin, J

Table of Contents Why GLP-1 Medications Cause Bloating Glucagon-like peptide-1 (GLP-1) receptor agonists including semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Saxenda, Victoza) are increasingly prescribed for type 2 diabetes management and weight loss

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GIP Agonism Reduces appetite, nausea, and bone resorption Increases insulin & glucagon production, and lipogenesis Glucagon Agonism Reduces appetite, food intake, and gastric emptying Increases insulin production, energy expenditure, and nausea Amylin Agonism Reduces appetite, food intake, glucagon production, and gastric emptying Increases energy expenditure Reduces bone resorption and increases bone production PYY Agonism Reduces appetite, food intake, and gastric emptying Increases energy expenditure and nausea The Cost Challenge for Payers The cost of GLP-1s continues to be a significant concern for payers between skyrocketing costs and utilization over the past several years