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Its downregulation contrasts with its ferroptosis-promoting role in other pathologies such as cancer, highlighting the context-dependent complexity of ferroptotic regulation

In stroke rats induced by thread embolism, catalpol regulates VEGF and VEGFR to activate the Notch signaling pathway, promoting angiogenesis and neural function remodeling without increasing tissue edema (Sun L

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Dietary polyphenols such as dihydromyricetin have also been documented to prevent ethanol-induced damage and improve ethanol-induced oxidative stress by regulating the expression of CYP2E1 and reducing ROS production [38]

Suppression of glucagon production GLP-1 agonists inhibit glucagon secretion from pancreatic alpha cells