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Full effects may vary depending on your B12 levels and overall health

21406065), the National High Technology Research and Development Program of China (Grant Nos

a Sir Henry Wellcome Trust Postdoctoral Research Fellowship (Grant 204727/Z/16/Z) to P.B

However, a significant proportion of patients are still refractory to pharmacological treatments, so the development of new drugs targeting the underlying mechanisms of UC is necessary to achieve optimal disease control

After incubation for 10 min, 200 L luciferin solution (containing 20 mM tricine, 1.0 mM MgSO4, 0.1 mM EDTA, 33 mM dithiothreitol, 270 M coenzyme A, 500 M D-luciferin, and 530 M ATP, pH 7.8) was added, and then the firefly luminescence was measured with a BioTek synergy 4 Multi-Mode Microplate Reader