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According to the available studies, DSIP is usually applied shortly before sleep onset due to its short half-life of just several minutes

Walden M, Tian L, Ross RL, Sykora UM, Byrne DP, Hesketh EL, et al

The formation of platinumDNA adducts mediates tumor cell necrosis or apoptosis, establishing these agents as the cornerstone of treatment for a wide range of solid tumors, including testicular cancer, ovarian cancer, lung cancer, and colorectal cancer (Johnstone et al

These interactions make DSIP a promising candidate for research on chronic pain and the mechanisms of dependence.DSIP and opioids, 1984, PMID 6548970