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Structural basis of prolyl hydroxylase domain inhibition by molidustat

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doi:10.1038/nrendo.2011.13 Wartofsky L, Dickey RA

Diverse naturally occurring compounds and dietary supplements (such as polyphenols, flavonoids, carotenoids etc) have been reported to be endowed with chemopreventive and angiopreventive activities in PCa [12, 13], by targeting multiple pathways, thus interfering with cancer insurgence, progression and metastasis [12,13,14,15]

Molybdenum-containing hydroxylases