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Some patients may suffer from high blood sugar, high cholesterol, or sleep apnea, with an altogether increased risk of more serious issues

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2, Additional file 1: S1, and S2), thereby sequestering Gfrom the receptors and G located on or near the plasma membrane [35]

Moreover, oxidative stress can enhance the expression of adhesion molecules and proteases, facilitating cancer cell detachment, invasion into surrounding tissues, and entry into the bloodstream [120]

Consequently, there may be a benefit to using GLP-1RA therapy as a neoadjuvant to promote an improved response in at least a subset of patients with cancer