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49 Secondly, its safety and efficacy remain unclear in patients with a history of pancreatitis as it has not been studied in this group

While the shortage of 1 mg Ozempic pens was resolved in Canada in early January, Novo Nordisk is expecting a shortage of its 0.25/0.5 mg pens until March

To date, the only advantage possessed by older weight loss medications is that they are often more accessible and affordable, though they are accompanied with varied side effects and decreased efficacy compared to GLP-1 and GLP/GIP medications

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Thus, following the identification of active BAT in adult humans and the demonstration that certain depots of white adipose tissue can undergo browning, there has been recent interest in the development of approaches that induce BAT activity and promote browning [10]