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SUSCEPTIBILIDAD A LAS DROGAS La biotransformacin heptica de las drogas comienza en el retculo endoplasmtico con la oxidacin por el citocromo P450 seguida de la conjugacin por las enzimas n-acetiltransferasa y glutationtransferasa, que produce metabolitos, denominados haptenos, que son ligados, posteriormente, a las protenas del hepatocito

Rolls, Marc-Andre Cornier, Jason R

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During thymic development of nTregs, the CNS2 region undergoes nearly complete DNA demethylation, which ensures the heritable stability of Foxp3 expression