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Participants were required to have a BMI between 28 and 38 kg/m 2 , to have an HbA1c concentration between 6.5 and 9%

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The experiment was performed in three independent replicates, significance analysis was performed through One-way ANOVA with Tukey multiple comparisons test, P value of 0 M versus 1 was 0.4751, 2.6 10 5 and 4.5 10 6 respectively, n.s

Reactive oxygen species promote TNF alpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases