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Thus, given the accumulating evidence across species implicating this pathway as integral to aging and its associated diseases, the development of therapeutics aimed at modulating IGF-1 signaling in humans could prove highly effective as a translational tool to delay aging

The co-culture system established with MCECs and MPMs is shown in Figure 4D

In 2026, manufacturer cash-pay programs from Novo Nordisk and Eli Lilly have slashed self-pay costs to $199$449 per month depending on the drug and dose

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