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PANCREAS ADVERSE EFFECTS Evidence based on recent studies The prevalence of various neuropsychiatric disorders is high in individuals with obesity [66]

In a retrospective cohort study of 16,827 patients in a single-center neuroophthalmology clinic, Hathaway et al found that semaglutide use was significantly associated with an increased incidence of NAION among patients with diabetes (HR = 4.28)

Diabetes 58 , 13121320 (2009)

In the SURMOUNT-4 trial, withdrawing tirzepatide after initial weight loss led to weight regain, while continued treatment maintained and extended weight reduction

Before use, may be stored at room temperature for up to 4 weeks per prescribing information For multi-dose pens, patients should write the date of first use directly on the pen using a permanent marker to track how long the medication has been in use